The Bioinformatics Institute Ghent From Nucleotides to Networks (BIG N2N) is a center of excellence in state-of-the-art bioinformatical tools and methods with applications in the fields of Sustainable Agriculture and Successful Ageing, recognized worldwide as key challenges for a sustainable society.
It was established as Multidisciplinary Research Partnership by Ghent University in 2011 as part of the strategic spearhead research policy plan promoting excellence in research, selected on the basis of the established expertise and the potential to become world leader in the field. Because of the growing importance of bioinformatics, computational biology, and systems biology in the life sciences, bioinformatics was one of the topics that were selected. In 2015 it was recognized as 'Bioinformatics Institute Ghent From Nucleotides to Networks'.
Colleague Pieter Mestdagh has been nominated for the biggest Science Talent of Belgium and The Netherlands by the New Scientist. Out of those 25 nominated people, 5 candidates will be for the final election in Amsterdam. Selection is based on the... Read more
Background: Genetic intratumoral heterogeneity (ITH) hinders biomarker development in metastatic clear cell renal cancer (mccRCC). Epigenetic relative to genetic ITH or the presence of consistent epigenetic changes following targeted therapy in... Read more
Unipept is an open source web application that is designed for metaproteomics analysis with a focus on interactive datavisualization. It is underpinned by a fast index built from UniProtKB and the NCBI taxonomy that enables quick retrieval of all... Read more
Shotgun proteomics experiments often take the form of a differential analysis, where two or more samples are compared against each other. The objective is to identify proteins that are either unique to a specific sample or a set of samples (... Read more