Network biology


The Cytoscape plug-in ‘Pathicular’ identifies path motifs in integrated networks and arranges them in a modular structure. After the integrated network and the source network (deletion or overexpression in this case) are loaded into Cytoscape, Pathicular can be used to find all the paths of a given type in the source network using the integrated network. A p-value is provided to check the overrepresentation of the path of interest.


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