Proteomics

Jun
20
Jun/20 11:00
Jozef Schell seminar room UGent-VIB Research Building FSVM Technologiepark 927 B-9052 Zwijnaarde (Gent)

BIG N2N seminar by Prof. Amos Bairoch: The human proteome: the neXtprot knowledge resource and other biocuration activities

We will describe the current status of neXtProt (www.nextprot.org), a web-based knowledge platform on human proteins. In particular we will discuss :

SFINX: Straightforward Filtering Index for Affinity Purification Mass Spectrometry Data Analysis

Affinity purification-mass spectrometry is one of the most common techniques for the analysis of protein-protein interactions, but inferring bona fide interactions from the resulting data sets remains notoriously difficult. We introduce SFINX, a Straightforward Filtering INdeX that identifies true-positive protein interactions in a fast, user-friendly, and highly accurate way. SFINX outperforms alternative techniques on two benchmark data sets and is available via the Web interface at http://sfinx.ugent.be/.

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