cancer

Apr
01
Apr/01 09:00 - Apr/02 18:00
Virginie Lovelingbuilding (VAC Gent) Koningin Maria Hendrikaplein 70 - 9000 Gent

From big data to bedside

Big datasets generated on the newest “omics” platforms significantly help in establishing a comprehensive view and understanding of tumor biology. At the same time, the handling and mining of these data sets poses great bioinformatic challenges. The complexity and size of these datasets is overwhelming and novel bioinformatic tools are being developed at a rapid pace to ensure fast and powerful analyses.

Jan
29
Jan/29 11:00 - Jan/29 12:00
Jozef Schell seminar room Technologiepark 927 B-9052 Gent

N2N seminar: Bioinformatics in cancer research

Cancer evolves dynamically as clonal expansions supersede one another, driven by shifting selective pressures, mutational processes, and disrupted cancer genes. These processes mark the genome, such that a cancer's life history is encrypted in the somatic mutations present. We are developing algorithms to decipher this narrative from whole genome sequencing data and are applying them to several cancer types. We call such approaches “molecular archaeology of cancer”, as we are using genomics and bioinformatics algorithms to infer a tumour’s evolutionary history.

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