Probabilistic motif detection requires a multi-step approach going from the actual de novo regulatory motif finding up to a tedious assessment of the predicted motifs. MotifSuite, a user-friendly web interface streamlines this analysis flow. Its core consists of two post-processing procedures that allow prioritizing the motif detection output. The tools offered by MotifSuite are built around the well-established motif detection tool MotifSampler but can also be used in combination with any other probabilistic motif detection tool.
MotifSuite: workflow for probabilistic motif detection and assessment. M. Claeys; V. Storms; H. Sun; T. Michoel; K. Marchal. Bioinformatics 2012; 28(14):1931-1932. doi: 10.1093/bioinformatics/bts293