Scientific programmer/Senior sequence data analyst

Department : Department of Human Genetics
Vacancy number : D.15.GJ.MV.18
Appointment : 36 hours per week
Starting date : as soon as possible
Educational requirements : bachelor
Maximum salary : according to CLA for University Hospitals
Closing date for applications : until the position is filled

The position

As a scientific programmer / (senior) sequence data analyst , you will conduct biomedical and clinical research in the LUMC by the analysis and interpretation of Next Generation Sequencing (NGS) data. You will develop and apply various analysis pipelines on large genome, exome and transcriptome data sets produced using advanced NGS technologies. You will contribute to the analysis and interpretation of data generated by novel NGS technologies such as Pacific Biosciences RSII single-molecule long read sequencing. Such projects can vary from characterizing full-length mRNA sequences to de novo characterization of fully phased variants in disease genes or de novo assembly and characterization of complex genomes or genomic regions. Other responsibilities include the integration of various omics datasets, such as exome-, transcriptome and chromatin immunoprecipitation sequencing data. This position will require and promote close collaboration with scientists from various fields.

The department

You will work within the department of Human Genetics at the LUMC. The focus of research of our group at the department of Human Genetics is to utilize NGS-based technologies to better understand the underlying mechanisms of diseases (such as muscular dystrophies, migraine, metabolic syndromes and cancer) and to improve healthcare. Automated processing and integration of high dimensional sequence-based data sets is currently the biggest challenge. Thus, you will be working together with a number of specialized teams within the LUMC and contribute to professionalize the support provided by the Technology Focus Area Bioinformatics and Biostatistics. Furthermore, you will be working together with multidisciplinary teams of laboratory specialists, medical doctors and ICT specialists.

Your profile

You have a Master's degree (or higher) in Computer Science with good knowledge of statistics and basic knowledge of molecular biology. Alternatively, you are a bioinformatician with at least two years of experience in the field. If you do not hold a Master’s degree but do feel that your profile and experience fits the requirements of this position, we advise you to send us your application for consideration. You must be a highly motivated and experimentally talented scientist with a drive to conduct your own research and answer important biomedical research questions. You have ample experience with programming languages like R and Python. Additionally, knowledge of command line scripting languages are desirable. You work in a structured way, using version control systems (like Git). You are flexible and communicative, are able to multitask and enjoy working in a multidisciplinary team.

We offer

You will be employed on the basis of a 36-hour week. A part-time appointment is possible as well. Appointment is for 1 year, with possibility for an extension. Your salary will depend on your qualifications and experience and according to the Collective Labour Agreement for University Hospitals.

The terms of employment offered by the LUMC are highly favorable. For example, you will receive an 8% holiday remuneration, a year-end bonus, and a pension arrangement with the National Civil Pension Fund. Also, as employee of one of the University Hospitals in the Netherlands, you can benefit from our collective health insurance policy.

Moreover, the LUMC offers excellent facilities in the area of education, child-care centers, and career advice.

More information

If you have any questions, of if you want more information about this position, please contact Jeroen Laros, senior researcher, Department of Human Genetics, email, telephone +31 (0)71 526 9504, or Yahya Anvar, postdoctoral researcher, Department of Human Genetics, email, telephone +31 (0)71 526 8559.
For this job, references will be requested.


If you are interested in this job and your satisfy the requirements in the job profile, we encourage you to apply. You can respond till the closing date. Please use the application form to apply (see

You can include annexes for example, your motivation letter or CV. You may rest assured that your details will be treated with strict confidentiality.

If we are planning to employ you, we will ask you for a Certificate of Good Conduct (VOG). The costs will be reimbursed

Contact information: 

Contact Jeroen Laros, senior researcher, Department of Human Genetics, email, telephone +31 (0)71 526 9504, or Yahya Anvar, postdoctoral researcher, Department of Human Genetics, email, telephone +31 (0)71 526 8559.

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