The Network Notif Clustering Toolbox is a Matlab/Octave toolbox for clustering topological network motifs in large-scale, integrated networks. The clustering algorithm is based on rigorous mathematical results and has been validated on an integrated yeast interaction network. See Michoel et al. for more information.
Michoel, T., Joshi, A., Nachtergaele, B. and Van de Peer, Y. (2010) Clustering of topological network motifs reveals common principles of transcriptional and posttranslational regulation in yeast.