BIG N2N Events

Feb 07

Systematic studies of cancer genomes are providing unprecedented insights into the molecular nature of human cancer. Using this information to guide the development and application of therapies in the clinic is challenging. Here we report how cancer-driving alterations identified in 11,289 tumors from 29 tissues (integrating mutations, copy-number alterations, methylation and gene expression) correlate with response to 265 compounds profiled in 1,001 human cancer cell-lines.

Mar 07

Jean-Philippe Vert is professor at the Department of Mathematics at Ecole normale supérieure of Paris, France, director of the Centre for Computational Biology (CBIO) at MINES ParisTech, and team leader at Institut Curie, Paris, France. He graduated from Ecole Polytechnique and has a PhD in mathematics from Paris 6 University. His main research interest is in machine learning and its application to biology, particularly cancer research.

Apr 25

Our group has been actively pursuing the idea that with great microscopes and great informatics we will be able to truly digitize models of cells, tissues, and organisms through time with information about the genetic and proteomic states of each cell layered there on. The belief is that these atlases combined with optical observations of labeled entities will accelerate the life sciences by allowing us to visualize these systems from any vantage point and as a system, thus leading to many discoveries such as the nature of the genetic control of fly wing development.